Update with ROS 7.1 also valid for EP06-e and EM-12-G cards.

From RouterOS v 7.1 Quectel cards are seen as LTE interface, hence all LTE bands in Australia are covered !

Wap R with EC25-AU card. Mikrotik RouterOS settings.

Firstly ensure direct IP is OFF:

/port firmware

set ignore-directip-modem=yes   

Reboot the Routerbord now

/port

set 0 name=usb1

/interface ppp-client

add apn=telstra.internet data-channel=3 dial-on-demand=no disabled=no info-channel=2 name=ppp-out1 port=usb1

The above settings are for Telstra with the below values of the channels:

Data channel: 3

Info channel: 2

Also, other popular APN for LTE in Australia:

Vodafone: live.vodafone.com

Optus: yesinternet

For quick and dirty way of having LTE interface instead of pppoe (30mbps limit) with EC25:

/port firmware set ignore-directip-modem=yes  -->  otherwise you won't be able to chane data and info channels and terminal into any other channel but 0
/system serial-terminal port=usb2 channel=2
AT+QCFG="usbnet",1
/port firmware set ignore-directip-modem=no
/system reboot

In case you want to go back to pppoe:

AT+QCFG="usbnet",0

For completeness, the USB integration modes available on the EC25 are:
AT+QCFG="usbnet",0 - is PPP & QMI (default)
AT+QCFG="usbnet",1 - is ECM.
AT+QCFG="usbnet",2 - is MBIM

if you need to get RSRP, SINR, or RSRQ from the module, then use:

AT+QENG="servingcell"

Also, very useful AT commands for changing QUECTEL EC25 configuration if you need to lock the EC25 to the B28 band:

AT+QCFG=“band”,0,8000000,0,1 

For any other bands hexadecimal value that specifies the LTE frequency bands, i.e. multiple bands can be selected by computing a logical OR of the individual value of each band (e.g.: 0x15 = 0x1(LTEB1)+0x4(LTE B3)+0x10(LTE B5)).

If set to 0 or 0x40000000 LTE frequency bands are not changed.

• 0x7FFFFFFFFFFFFFFF means all available bands will be used
• 0x1 LTE B1
• 0x4 LTE B3
• 0x10 LTE B5
• 0x40 LTE B7 
• 0x80 LTE B8
• 0x80000 LTE B20
• 0x7FFFFFFFFFFFFFFF Any frequency band (default setting)  - apparently this is not working with Mikrotik Routerboard, below is the new command that works 

Lock EC25 to Band3 command:

at-chat lte1 input=“AT+QCFG=\“band\”,0,4444,0,1”

All bands command that works with EC25 inside Mikrotiks:

at-chat lte1 input=“AT+QCFG=\“band\”,0,7777777,0,1” 

HOW TO find the band the modem is currently on:

at-chat lte1 input=“AT+QNWINFO”